Breakfast, Exercise and Metabolic Health in Healthy Men

National Taiwan Normal University

Status: Enrolling

Conditions: Appetitive Behavior; Metabolic Health; Energy Balance

Treatments: Behavioral: High carbohydrate breakfast exercise; Behavioral: High protein breakfast exercise; Behavioral: Fasted exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05291065

202012HM031

Details and patient eligibility

About

This project aims to investigate the impact of acute bout of submaximal exercise under different pre-exercise dietary conditions (fasted state versus high carbohydrate breakfast versus high protein breakfast) on postprandial glycaemic, appetite regulation and energy balance.

Full description

Participants will be asked to arrive to the laboratory between 08:00 and 9:00 am after not eating for between 12-14 hours i.e. in a fasted state (water intake is permitted and encouraged). Participants will then be given one of three test drinks (i.e., breakfast): 1) water only; 2) high carbohydrate drink; or 3) high protein (whey protein) drink. Each of these drinks will also contain 500 mL of water and artificial sweetener. 2 h after breakfast, participants will then exercise on a treadmill for 45 min followed by a 2-h oral glucose tolerance test (OGTT) and 30 min ad libitum lunch intake. Blood samples, blood pressures and questionnaire (e.g., appetite and mood) will be collected in a regular pattern throughout the trials. Cognitive functions will be tested at baseline, pre-exercise and 2 h post-exercise. Energy balance will be assessed using food diary and an accelerometer for the rest of the day after leaving the laboratory until midnight.

Enrollment: 12 estimated patients

Sex: Male

Ages: 30 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy physical active men (self-reported regular exercise at least 30 min moderate-intensity 3 times per week)
• Aged between 30 to 55 years
• Weight stable for more than 3 months (no change in weight +/- 3%)
• Non-smoker

Exclusion criteria

• Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
• Taking medications that may influence lipid or carbohydrate metabolism or immune system function
• Women
• Physically inactive

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 3 patient groups

Fasted exercise

Experimental group

Description:

Fasted prior to exercise

Treatment:

Behavioral: Fasted exercise

High protein breakfast exercise

Experimental group

Description:

High protein breakfast consumption prior to exercise

Treatment:

Behavioral: High protein breakfast exercise

High carbohydrate breakfast exercise

Experimental group

Description:

High carbohydrate breakfast consumption prior to exercise

Treatment:

Behavioral: High carbohydrate breakfast exercise