Breast Tumour Size Measurement by Field Cycling Imaging (BREVIA)

University of Aberdeen

Status: Not yet enrolling

Conditions: Breast Cancer; Ductal Carcinoma In Situ

Treatments: Other: Field-Cycling Imaging research scan; Other: 3T MRI research scan

Study type: Observational

Funder types: Other

Identifiers

NCT07492043

2-082-25

25/NW/0355 (Other Identifier)

Details and patient eligibility

About

The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can accurately estimate tumour size in patients with a type of breast cancer called ductal carcinoma in situ (DCIS). The main question it aims to answer is:

Can FCI accurately estimate DCIS lesion size compared with histology results?

Participants will have a standard MRI scan and an FCI scan before undergoing surgery to remove the tumour.

Enrollment: 12 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Females ≥ 18 years old.
• Subjects diagnosed with DCIS on initial biopsy.
• Lesion size >1 cm on imaging.
• Subjects undergoing surgery as part of their treatment.
• Able to fit comfortably in the scanners.
• Able to understand written and spoken English.

Exclusion criteria

• Subjects undergoing chemotherapy or hormonal therapy.
• Individuals unable to give informed consent.
• Contra-indications to MRI scanning such as implantable cardiac devices.
• Known allergy to contrast agent.

Trial design

12 participants in 1 patient group

Breast Cancer

Description:

Participants with breast cancer of ductal carcinoma in-situ (DCIS) who are due to undergo surgical treatment.

Treatment:

Other: 3T MRI research scan

Other: Field-Cycling Imaging research scan