Breath Analysis Based Disease Biomarkers

Mayo Clinic

Status: Completed

Conditions: COVID19; Liver Cancer; Liver Diseases

Treatments: Diagnostic Test: Collection of breath sample

Study type: Observational

Funder types: Other

Identifiers

NCT04341012

19-001971

Details and patient eligibility

About

The purpose of the study is to develop a clinical test based on breath analysis that can be used for disease diagnosis or prognosis.

Full description

The study will seek to collect and analyze breath samples from a broad range of patients to develop reference ranges and to refine the testing methods. Protocols for breath sample collection and algorithms for analysis will be developed. Samples will be collected from normal volunteers, persons with documented liver disease, organ transplant or with known COVID-19 test results.

Enrollment: 46 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Able to provide informed consent

Exclusion criteria

• None

Trial design

46 participants in 4 patient groups

Normal

Description:

No known medical conditions

Treatment:

Diagnostic Test: Collection of breath sample

Liver Cirrhosis

Description:

Clinically diagnosed with cirrhosis

Treatment:

Diagnostic Test: Collection of breath sample

COVID-19 tested

Description:

Persons with known test results for COVID-19 RNA

Treatment:

Diagnostic Test: Collection of breath sample

Other

Description:

Persons with other medical diagnosis, no known liver disease, negative for COVID-19

Treatment:

Diagnostic Test: Collection of breath sample