Breath Analysis by Ion Mobility Spectrometry

Lung Clinic Hemer

Status: Enrolling

Conditions: Lung Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT00632307

lkhemer1-2008

Details and patient eligibility

About

Recognition of disease specific clusters of volatile organic compounds in patients with different lung diseases, using breath analysis with ion mobility spectrometry. Lung diseases of interest are:

• COPD
• tumors
• airway infection
• interstitial lung disease
• sleep apnea Hypothesis: Breath analysis with ion mobility spectrometry can differentiate pulmonary disorders.

Full description

Recruitment of patients with different lung diseases goes on. First sub-group analysis of patients with COPD,lung cancer and sarcoidosis is done in order to create a training set of VOC-clusters for further validation in a bigger population of patients.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Any patient
• Ages 18-90 years old

Exclusion criteria

• Patient who are not able to perform an exhalation manoever.

Trial design

1,000 participants in 8 patient groups

1

Description:

COPD

2

Description:

lung cancer

3

Description:

airway infection

4

Description:

interstitial lung disease

5

Description:

sleep apnea

6

Description:

pulmonary disorders with pleural infusions

7

Description:

sarcoidosis

8

Description:

healthy persons