Breath Analysis in Healthy Controls

University of Zurich (UZH)

Status: Completed

Conditions: Mass Spectrometry; Healthy Subjects; Exhaled Breath

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02595632

KEK-ZH-Nr. 2015-0187

Details and patient eligibility

About

The purpose of this study is to detect a specific profile of breath in healthy subjects by an untargeted metabolomic study using exhaled breath analysis by mass spectrometry.

Enrollment: 183 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Normal spirometry (forced expiratory volume in 1 second (FEV1) > 80%, forced vital capacity (FVC) > 80%, FEV1/FVC > 70%.).
2. Age between 18 and 90 years at study entry.

Exclusion criteria

1. Presence of an active malignancy.
2. Presence of any lung disease (e.g. asthma, chronic obstructive pulmonary disease (COPD), sarcoidosis)
3. Acute inflammatory disease (e.g. common cold) within the last 6 weeks.
4. Acute or chronic hepatic disease.
5. Renal failure or renal replacement therapy.

Trial design

183 participants in 1 patient group

Healthy

Description:

Healthy subjects with no apparent lung disease and normal lung function testing.

Treatment:

Other: No intervention