Breath Analysis to Diagnose Lung Cancer (CATOCOV)

University Hospital, Lille

Status: Completed

Conditions: Lung Cancer

Treatments: Device: Collection of volatile organic compounds during exhalation

Study type: Interventional

Funder types: Other

Identifiers

NCT03250390

2017-A00932-51 (Other Identifier)

2017_05

PHRCI_2016 (Other Identifier)

Details and patient eligibility

About

Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.

Enrollment: 1,500 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with histologically proven lung cancer

Controls:

• healthy smoker or non-smoker subjects
• without respiratory diseases excepted chronic obstructive pulmonary disease.

Exclusion criteria

• history of cancer other than lung cancer within 5 years before inclusion
• oral or facial malformation
• incomprehension of maneuvers for the collection

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

1,500 participants in 2 patient groups

patients

Experimental group

Description:

Patients with bronchopulmonary cancer who have not yet received therapeutic treatment.

Treatment:

Device: Collection of volatile organic compounds during exhalation

controls

Active Comparator group

Description:

The controls consisted of 2 groups: smokers and non-smokers.

Treatment:

Device: Collection of volatile organic compounds during exhalation