Breath Gas Analysis for the Diagnosis of Breast Cancer

Ionimed Analytik

Status: Terminated

Conditions: Mamma Carcinoma

Treatments: Device: Breath Collecting Unit

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01105468

BC1

Details and patient eligibility

About

The volatile content of the exhaled breath gas of mamma carcinoma patients will be chemically analyzed by proton-transfer-reaction time of flight mass spectrometry.

The goal of the study is to determine typical breath gas components that allow to distinguish patients with mamma carcinoma from women without carcinoma. Further, the investigators will test whether these breath gas markers can be used as tumor markers, which change in a typical manner during the progress of the disease. Finally the data will be investigated for the presence of marker components, that identify patients who will develop metastasis.

Enrollment: 202 patients

Sex: Female

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Mamma carcinoma diagnosed by histology (cases)
• Mamma carcinoma excluded by radiology (controls)
• At the time of diagnosis before surgery
• At the beginning and during chemotherapy;

Exclusion criteria

• No informed consent form singed

Trial design

202 participants in 3 patient groups

Mamma Carcinoma, no treatment

Treatment:

Device: Breath Collecting Unit

Device: Breath Collecting Unit

Mamma Carcinoma, treatment

Treatment:

Device: Breath Collecting Unit

Device: Breath Collecting Unit

No Mamma Carcinoma diagnosed by X-ray

Treatment:

Device: Breath Collecting Unit

Device: Breath Collecting Unit