Breath-hold Cardiac Hybrid SPECT/CCTA

University of Zurich (UZH)

Status: Completed

Conditions: Coronary Artery Disease

Treatments: Device: Breathhold SPECT-MPI; Device: Coronary CT angiography; Device: Standard freebreathing SPECT-MPI

Study type: Interventional

Funder types: Other

Identifiers

NCT02469051

USZ-2015-0098

Details and patient eligibility

About

This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Referral for cardiac hybrid SPECT/CCTA
• Male and female subjects 18 years of age or older
• Written informed consent by the participant after information about the project

Exclusion criteria

• Contraindications for coronary CT angiography (including renal failure with a GFR <30ml/min/1.73m2, allergies to iodinated contrast agents)
• Pregnancy or breast-feeding
• Previous coronary revascularisation
• Inability to follow the examination procedure (e.g. due to language barriers, severe mental disease etc

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI

Other group

Treatment:

Device: Breathhold SPECT-MPI

Device: Standard freebreathing SPECT-MPI

Device: Coronary CT angiography