BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma (BROTHER)

University Medical Center Groningen (UMCG)

Status: Terminated

Conditions: Esophageal Cancer

Treatments: Other: DIBH using VC technique; Other: DIBH using ABC technique

Study type: Interventional

Funder types: Other

Identifiers

NCT06317272

RT2016-04-BROTHER Part 1

Details and patient eligibility

About

The main objective of the first part of the study is to determine the most optimal method for DIBH (active breathing control vs voluntary coached) and its reproducibility. Based on these findings, one of these methods will be selected for part 2 of this study.

Enrollment: 1 patient

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically proven esophageal cancer of the mid or distal esophagus
• Scheduled for external-beam photon radiotherapy with curative intention.
• WHO 0-2.
• Age >= 18 years
• Written informed consent.

Exclusion criteria

• Serious respiratory distress
• Contra-indication for fiducial marker placement
• Noncompliance with any of the inclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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1 participants in 2 patient groups

ABC DIBH

Active Comparator group

Description:

Active Breathing Controlled (ABC) technique for deep breath inspiration hold (DIBH)

Treatment:

Other: DIBH using ABC technique

VC DIBH

Experimental group

Description:

Voluntary Coached (VC) technique for deep breath inspiration hold (DIBH)

Treatment:

Other: DIBH using VC technique