Bright Light as a Countermeasure for Circadian Desynchrony

VA Palo Alto Health Care System

Status: Unknown

Conditions: Healthy

Treatments: Other: Bright light

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT01119365

10165 (Registry Identifier)

Details and patient eligibility

About

Light is the primary means by which the internal circadian clock remains aligned ("entrained") with the external world. Misalignment of this internal clock can occur during situations such as shift work and jet travel across multiple time zones (jet lag). The purpose of this study is to examine how sequences of brief flashes of light can affect entrainment of the clock.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Good health
• Normal hearing

Exclusion criteria

• Sleep disorder
• Extreme chronotype
• Regular smoker
• Depression
• Alcohol abuse
• Illegal drug use

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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300 participants in 1 patient group

Light

Experimental group

Description:

Sequence of bright light flashes of varying durations, interflash intervals, flash lengths, flash brightness, and flash color.

Treatment:

Other: Bright light