Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD

Erica Osborn

Status: Terminated

Conditions: Depressive Symptoms; Chronic Obstructive Pulmonary Disease; Cystic Fibrosis

Treatments: Device: Bright Light Therapy (BLT) Lamp

Study type: Interventional

Funder types: Other

Identifiers

NCT04921332

STUDY20110407

Details and patient eligibility

About

This is a project that will determine whether the use of daily bright light therapy has an effect on depressive symptoms experienced by adult inpatients with CF and COPD. The purpose of this project is to apply a daily 30-minute BLT intervention to hospitalized adult CF and COPD patients in order to decrease symptoms of depression as measured by depression inventory scoring.

Full description

This project will occur on a 29-bed pulmonary step-down unit at a 1,600-bed academic medical center. This unit commonly treats patients with CF, COPD, and other pulmonary complications. The unit's patient care staff will be educated on the bright light lamps in order to prevent interruptions and to encourage compliance.

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with cystic fibrosis or chronic obstructive pulmonary disease (COPD)
• Adult age 18 or older
• Admitted to the pulmonary step-down and transplant unit
• Score greater than zero on pre-intervention Beck's Depression Inventory-II (BDI-II)

Exclusion criteria

• Pre-existing ophthalmological conditions or photosensitivity
• Migraines
• Receiving high dose steroids for transplant rejection (due to mood altering qualities),
• Antibiotics that increase light sensitivity
• Diagnosed with bipolar disorder (light therapy may trigger mania)
• Admissions anticipated to span less than 48 hours
• Children are being excluded due to the fact that only adult CF and COPD subjects are admitted to University of Pittsburgh Medical Center (UPMC) Presbyterian hospital

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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4 participants in 1 patient group

Bright Light Therapy (BLT)

Experimental group

Description:

The intervention will consist of daily BLT sessions lasting 30 minutes at approximately 10AM (since many CF and COPD patients may not awaken until this time) starting on the day of admission through discharge for a goal of seven consecutive days. The intervention will use a 10,000-lux light box placed approximately 16-24 inches from the patient's face.

Treatment:

Device: Bright Light Therapy (BLT) Lamp