Bright Light Therapy on Sleep Health in Lung Cancer Patients (BLT)

Henry Ford Health

Status

Enrolling

Conditions

Lung Cancers

Treatments

Other: bright light

Study type

Interventional

Funder types

Other

Identifiers

NCT07064395

17849

F80046 (Other Grant/Funding Number)

Details and patient eligibility

About

The goal of this randomized intervention trial is to determine the effect of bright light therapy on sleep disturbance, as well as to investigate the impacts of bright light therapy on biological age measured by clinical biomarkers. The main questions it aims to answer are:

Does bright light therapy improve sleep patterns (i.e., sleep onset latency, sleep disturbance, and sleep efficiency) in lung cancer patients?
Can bright light therapy slow the rate of aging measured by biological age in lung cancer patients? Researchers will compare bright light therapy group to control group to see if bright light works to reduce sleep disturbance and decelerate biological aging.

Participants will:

Receive bright light exposure or usual light exposure every day for 4 weeks
Get blood draw at the baseline and at 4 weeks for clinical biomarkers tests
Complete self-reported sleep, fatigue and stress surveys at the baseline and at 4 weeks
Keep a daily sleep log

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

>=18 years of age
Stage Ib to IIIb primary lung cancer diagnosis
>=2 months after completion of primary therapy, patient can continue to be on maintenance/immunotherapy
ECOG performance status is 0 or 1
Experience problematic sleep (scores of >=8 on the Insomnia Severity Index)
Able to understand, speak, and read English
Sighted and mentally competent to consent

Exclusion criteria

Pregnant women
Have metastatic cancer
on oxygen therapy
Current diagnosis of seasonal affective disorder or substance abuse
Engage in shift work or travel across >3 time zones within 2 weeks prior to the study
Are currently being treated for sleep apnea, restless legs syndrome, or narcolepsy
Take prescribed sedative hypnotics or antipsychotics
Have eye conditions (glaucoma or retinal disease), problem triggered by bright light (e.g., migraine), or take photosensitizing medications (e.g., some porphyrin drugs, antipsychotics, antiarrhythmic agents)
Participants with an Insomnia Severity Index <8
Participants with cognitive impairment (sores of <3 mini-cog test)