Brimonidine in Rosacea

Cairo University (CU)

Status: Not yet enrolling

Conditions: Rosacea

Treatments: Other: treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT05401422

Rosacea

Details and patient eligibility

About

Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide.

Full description

In our study, we will compare the safety, efficacy, and adverse effects of low-dose oral doxycycline alone versus combined with pulsed dye laser or topical brimonidine in treating erythematotelangiectatic rosacea in an attempt to build a treatment strategy in a disease with complex pathogenesis.

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with current erythematotelangiectatic rosacea

Exclusion criteria

• Pregnant females. 2-Patients on systemic steroids. 3-Patients complaining of other dermatological disorders mainly photosensitive cutaneous disorder.

4- Patients receiving any systemic treatment including retinoids for the previous 1 month or any topical treatment for the previous 2 weeks or any laser sessions for the previous 3months for erythematotelangiectatic rosacea at least.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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45 participants in 3 patient groups

Pulsed dye laser

Active Comparator group

Description:

Laser

Treatment:

Other: treatment

Doxycycline

Active Comparator group

Description:

Drug

Treatment:

Other: treatment

Brimonidine gel 0.33%

Active Comparator group

Description:

Topical drug

Treatment:

Other: treatment