Bronchoscopic Role in Early Detection of Endobronchial Tuberculosis in Suspected Pulmonary Tuberculosis Patients.

Ain Shams University

Status: Completed

Conditions: Tuberculosis, Pulmonary; Endobronchial Mass

Treatments: Diagnostic Test: fiberoptic bronchoscopy evaluation of endobronchial features of TB

Study type: Observational

Funder types: Other

Identifiers

NCT07350356

FMASU MD 203/2023

Details and patient eligibility

About

The aim of the present study is to evaluate the role of bronchoscopy in diagnosis of endobronchial tuberculosis in suspected pulmonary tuberculosis patients whose sputum samples are negative for Ziehl Neelsen stain.

Full description

Bronchoscopy plays a major role in identification and diagnosis of EBTB. As a general principal, Bronchoscopy -associated with microbiological testing- must be performed on patients whose CT examination results indicate EBTB.

This study will try to focus on the importance of bronchoscopy in diagnosis of endobronchial tuberculosis among suspected pulmonary tuberculosis patients who undergo fiberoptic bronchoscope after being sputum Ziehl Neelsen negative, scarce sputum and/or persistent consolidation on chest radiograph (CXR).

Enrollment: 63 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• o Adults more than18 years.

  • Accept to participate.
  • Suspected pulmonary tuberculosis patients with three negative sputum samples are smear negative, and/or persistent consolidation on chest radiograph (CXR).

Exclusion criteria

• o Patients who refuse to participate in the study.

  • Patients who are sputum Ziehl Neelsen positive.
  • Patients who are diagnosed extrapulmonary tuberculosis.
  • Patients who are not fit for bronchoscopy.

Trial design

63 participants in 1 patient group

group 1: PTB with concomitant EBTB, group 2: PTB with no concomitant EBTB.

Description:

group 1of 41 patients had positive bronchoscopic findings of PTB with concomitant of EBTB, group 2 of 22 patients had PTB with no concomitant EBTB.

Treatment:

Diagnostic Test: fiberoptic bronchoscopy evaluation of endobronchial features of TB