Brucella Serology and History of Brucellosis in Patients With Modic Changes Type 1

Veysel Delen

Status: Completed

Conditions: Brucellosis; Spinal Degeneration

Treatments: Other: Medical history for brucellosis; Other: Brucella serology test

Study type: Observational

Funder types: Other

Identifiers

NCT04911283

SUEADH

Details and patient eligibility

About

Objective: This study aims to examine Brucella serology and history of brucellosis in patients with lumbar Modic changes (MCs) type 1, considering results from cross-sectional and case-control comparisons.

Design: In comparative cross-sectional design, MCs type 1 patients (study group) and MCs type 2 patients (comparator group) were examined in terms of Brucella serology by using agglutination with Coombs test. In addition, in comparative case-control design, both of the MCs groups and age/sex-matched healthy controls were investigated for their medical history regarding brucellosis.

Enrollment: 118 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with lumbar Modic changes type 1
• Patients with lumbar Modic changes type 2
• Participant who given informed consent for the study

Exclusion criteria

• Patients aged<18 years
• History of serious lumbar trauma
• Lumbar spinal surgery
• Scoliosis
• Cooperation disorder

Trial design

118 participants in 3 patient groups

MCs type 1 patients (study group; n=37)

Treatment:

Other: Medical history for brucellosis

Other: Brucella serology test

MCs type 2 patients (comparator group; n=44)

Treatment:

Other: Medical history for brucellosis

Other: Brucella serology test

healthy controls (n=37)

Treatment:

Other: Medical history for brucellosis