Bubble Continuous Positive Airway Pressure (CPAP) With Conventional CPAP for Extubation in Preterm Infants

All India Institute Of Medical Science (AIIMS)

Status

Completed

Conditions

Extubation Failure

Treatments

Device: Conventional CPAP

Device: Bubble CPAP

Study type

Interventional

Funder types

Other

Identifiers

NCT00979433

A-74

Details and patient eligibility

About

The objective of this study is to evaluate whether CPAP delivered by bubble CPAP resulted in a greater proportion of infants being successfully extubated when compared with management with ventilator derived CPAP.

Full description

There have been no published randomized trials comparing extubation failure rates of Bubble CPAP with conventional ventilator derived CPAP. Infants of gestation <32 weeks and of birth weight less than 1500 grams considered by the treating team to be ready for the initial extubation within first week of life were screened for enrolment. All eligible neonates were randomly allocated to bubble CPAP or conventional CPAP.The purpose of this study is to compare whether infants on Bubble CPAP had more chances of successful extubation as compared to infants put on Conventional CPAP.

Enrollment

32 patients

Sex

All

Ages

Under 7 days old

Volunteers

No Healthy Volunteers

Inclusion criteria

Gestation less than 32 weeks
Birth weight less than 1500 g
Age less than seven days
First extubation attempt.

Exclusion criteria

A neonate having any of the following will be excluded from the study-
Severe birth asphyxia defined as need for chest compression for more than 30 seconds
Suspected congenital neuromuscular disorder
Major congenital malformation
Grade 3/4 interventricular haemorrhage
Hydrops.