Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.

Cairo University (CU)

Status: Unknown

Conditions: Pelvi Ureteric Junction Obstruction or Ureteral Stricture

Treatments: Procedure: buccal mucosal graft to repair iatrogenic PUJO

Study type: Interventional

Funder types: Other

Identifiers

NCT04503330

cairo univeristy

Details and patient eligibility

About

Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.

Full description

A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter.

after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis.

Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.

Enrollment: 20 estimated patients

Sex: All

Ages: Under 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture

Exclusion criteria

• elderly patients unfit for general anaesthesia.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Patients with iatrogenic PUJO

Experimental group

Description:

patients with iatrogenic PUJO or long segment ureteric stricture disease for safety and efficacy of using buccal graft for repair

Treatment:

Procedure: buccal mucosal graft to repair iatrogenic PUJO