Buerger-Allen Exercises and Peripheral Circulation in Sedentary Office Workers (BAE-CIRC)

Istanbul Gelisim University

Status: Begins enrollment this month

Conditions: Peripheral Circulation; Vascular Function; Sedentary Behavior

Treatments: Behavioral: Buerger-Allen Exercise Program

Study type: Interventional

Funder types: Other

Identifiers

NCT07588893

2209A-2025Fall-Submitted (Other Identifier)

IGU-FTR-BAE-2026-001

Details and patient eligibility

About

This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers. Prolonged sitting is associated with reduced venous return, impaired peripheral circulation, and endothelial dysfunction. Buerger-Allen exercises are simple position-based exercises designed to enhance arterial blood flow, venous return, and tissue perfusion. Thirty-five healthy sedentary adults aged 18 to 45 years will participate in this single-group pretest-posttest clinical trial. Skin surface temperature, capillary refill time, ankle-brachial index, peripheral oxygen saturation, and heart rate will be measured before and after a single 20-minute exercise session. The findings may support the use of Buerger-Allen exercises as a practical, low-cost physiotherapy strategy to improve peripheral circulation and reduce the adverse vascular effects of prolonged sitting.

Full description

Sedentary behavior and prolonged sitting are associated with impaired venous return, reduced peripheral blood flow, endothelial dysfunction, and increased cardiovascular risk. Office workers who remain seated for extended periods may experience lower extremity discomfort, edema, and early circulatory impairment.

Buerger-Allen exercises are position-based therapeutic exercises that involve sequential elevation, dependency, and horizontal rest of the lower limbs. These exercises are designed to promote arterial inflow, facilitate venous return, and enhance tissue perfusion without requiring specialized equipment. Previous studies have demonstrated beneficial effects in patients with peripheral vascular disease and diabetes, but evidence regarding their acute effects in healthy sedentary adults is limited.

This study will use a quasi-experimental single-group pretest-posttest design to investigate the immediate effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers. A total of 35 participants aged 18 to 45 years will be recruited from Istanbul Gelisim University. All participants will complete a standardized 20-minute Buerger-Allen exercise protocol.

Primary outcome measures will include skin surface temperature assessed with infrared thermometry, capillary refill time, ankle-brachial index, peripheral oxygen saturation, and heart rate. Measurements will be performed at baseline, immediately after the intervention, and 10 minutes after the intervention.

The study is expected to provide evidence regarding the effectiveness of a simple and low-cost physiotherapy intervention for improving peripheral circulation and preventing the adverse vascular effects associated with prolonged sedentary behavior.

Enrollment: 35 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy sedentary office workers
• Age between 18 and 45 years
• Sitting for at least 6 hours per day for work-related activities
• Not meeting regular physical activity recommendations
• Willing to participate voluntarily and provide written informed consent

Exclusion criteria

• History of peripheral arterial disease, deep vein thrombosis, or other vascular disorders
• Cardiovascular, neurological, or musculoskeletal conditions that may affect lower extremity circulation or prevent exercise participation
• Diabetes mellitus
• Current smoking
• Pregnancy
• Use of medications that may significantly affect peripheral circulation
• Lower extremity injury or surgery within the previous 6 months
• Participation in regular structured exercise programs

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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35 participants in 1 patient group

Buerger-Allen Exercise Group

Experimental group

Description:

Participants will perform a single standardized 20-minute Buerger-Allen exercise session. Lower extremity circulatory parameters will be assessed before the intervention, immediately after the intervention, and 10 minutes after the intervention.

Treatment:

Behavioral: Buerger-Allen Exercise Program