BUMPP: A Study to Better Understand Mood During the Perinatal Period

University of Minnesota (UMN)

Status: Completed

Conditions: Mental Health Issue; Postpartum; Pregnancy

Treatments: Other: Observation Group

Study type: Observational

Funder types: Other

Identifiers

NCT05537259

CEHD-2023-31101

Details and patient eligibility

About

The overall goal of the BUMPP study is to improve our understanding of a range of moods, feelings, and thoughts that women can experience during pregnancy and soon after they give birth. This study will examine how these moods, feelings, and thoughts are related to changes in hormonal and immune health that women experience during and after pregnancy, and to mother-baby relationships and infant development in the early postpartum months.

Enrollment: 168 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years or older
• 35 weeks pregnant or less
• carrying only one baby (not twins or triplets)
• first time giving birth
• can speak/read/write in English

Exclusion criteria

• major medical health condition like a heart, kidney, or liver disease or HIV
• currently taking corticosteroids, progesterone, or immunosuppressive medications that might impact the samples we are taking in this research study
• have regularly used alcohol, tobacco, or recreational drugs (such as marijuana or prescription drugs for non-medical reasons) during pregnancy (regularly means more than a few times total, such as on a monthly, weekly, or daily basis)

Trial design

168 participants in 1 patient group

Observation Group

Description:

Researchers will collect data on maternal mental health symptoms, as well as health and psychosocial factors, via short interviews (sessions 1 and 4) and via self-report questionnaires completed through REDCap at each session. Participating women will also provide one small hair sample (session 4) for measurement of the stress hormone cortisol and several finger stick blood spot samples (sessions 1,2, and 4) for measurement of immune markers.

Treatment:

Other: Observation Group