Bupivacaine Epiphora Trial

McMaster University

Status and phase: Withdrawn; Phase 2

Conditions: Ptosis; Epiphora

Treatments: Drug: 0.75% bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT03266081

HS#: 14-00614

Details and patient eligibility

About

The objective of this study is to investigate quantitative improvement in excessive tearing after administration of Bupivacaine, a local anesthetic, into the affected eyelids.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients age 18 and above, patients with unilateral or bilateral excessive tearing.

Exclusion criteria

Pregnant females, vulnerable populations, patients with severe hepatic disease, or patients using monoamine oxidase inhibitors or tricyclic antidepressants, which are contraindicated with bupivacaine and norepinephrine combinations.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

0.75% bupivacaine

Experimental group

Treatment:

Drug: 0.75% bupivacaine