Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI

Research Institute of Ophthalmology, Egypt

Status and phase: Completed; Early Phase 1

Conditions: Pain, Acute

Treatments: Drug: bupivacaine 0.5% and oxubuprocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05069350

Topical anesthesia in IVI

Details and patient eligibility

About

comparing two local anaesthetic agents, Bupivacaine 0.5% versus Oxybuprocaine used topically to provide surface anaesthesia before IVI procedures.

Full description

In preparation zone, we will cannulate the patients, connect them to the pulse oximetry and we will start providing appropriate surface anaesthesia for an adequate period of time before the patient administration of the injection, by applying the anaesthetic agents, 3 times with 5 minutes interval, for 15 minutes and then waitng the injection

All patients are informed that they are going to receive topical anaesthetic agent before the IVI.

pain is monitored during the injection by using the 11 points verbal numerical pain scaling as zero is for no pain and 10 is for severe unbearable pain.

Enrollment: 100 patients

Sex: All

Ages: 30 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All patients between 30 to 70 years

Exclusion criteria

• uncooperative patients

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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100 participants in 2 patient groups

bupivacaine 0.5%

Experimental group

Treatment:

Drug: bupivacaine 0.5% and oxubuprocaine

oxybuprocaine

Experimental group

Treatment:

Drug: bupivacaine 0.5% and oxubuprocaine