Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block in Caesarean Section

Menoufia University

Status: Completed

Conditions: Post Operative Pain

Treatments: Procedure: Transversus Abdominis Plane Block with bupivacain Plus dexamethasone; Procedure: Transversus Abdominis Plane Block with bupivacain

Study type: Interventional

Funder types: Other

Identifiers

NCT06292273

ANET19

Details and patient eligibility

About

Transversus Abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic surgeries such as caesarean section, hysterectomy, appendicectomy and various laparoscopic surgeries. this study is conducted to analyse the effect of addition of dexmedetomidine to bupivacaine in Transversus Abdominis Plane (TAP) block.

Full description

Peripheral nerve block is becoming increasingly popular technique for postoperative pain relief and is also established as a part of multimodal analgesia and enhanced recovery program. Transversus abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic surgeries such as caesarean section, hysterectomy, appendicectomy and various laparoscopic surgeries.The Purpose of a TAP block is to infiltrate local anaesthetic agents in the plane between the internal oblique and transversus abdominis muscles thereby providing effective postoperative analgesia. Earlier the blind TAP block (through lumbar triangle of Petit) was commonly given but with widespread use of ultrasound nowadays it is almost always given under ultrasound guidance. Accuracy and efficacy of TAP block is significantly improved under ultrasound guidance because under ultrasound guidance the anesthetic agent can be properly deposited in the neurovascular plane. Ultrasound provides real time and direct visualisation of needle during infiltration of local anaesthetic drug.

Enrollment: 60 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• pregnant female elected for cesarean section
• ASAll

Exclusion criteria

• coagulopathy

• BMI>35

  • heart Diseases
  • diabets

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Group Bupivacain Plus dexamethasone

Active Comparator group

Description:

receiving plain bupivacaine 0.1%, 35 ml with dexmedetomidine 0.5

Treatment:

Procedure: Transversus Abdominis Plane Block with bupivacain Plus dexamethasone

Group bupivacain

Placebo Comparator group

Description:

plain bupivacaine 0.25%, 25 ml bilaterally

Treatment:

Procedure: Transversus Abdominis Plane Block with bupivacain