BUPrenorphine Facilitated Access and Supportive Treatment --AIM 3 (BUPFAST)

Montefiore Medicine Academic Health System

Status: Terminated

Conditions: Opioid-related Disorders

Treatments: Behavioral: BUP_FAST; Behavioral: Referral to treatment

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02902835

2016-6559

K23DA034541 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of this study is to test whether peer mentors (i.e., individuals with past opioid addiction and prior incarceration) can facilitate entrance into buprenorphine (Suboxone) treatment for individuals with opioid use disorder who were recently released from jail or prison. In order to test whether it is helpful to have peer mentors paired with recently released individuals, the investigators will conduct an 18 month study, recruiting 72 formerly incarcerated individuals and assigning them by chance selection (like flipping a coin) to either a group that will receive peer mentorship or a group that will receive a referral to a community clinic.

Full description

BUPrenorphine Facilitated Access and Supportive Treatment (BUP-FAST) is a peer mentorship intervention in which trained peer mentors will link formerly incarcerated individuals with opioid use disorder to addiction treatment (i.e. buprenorphine maintenance treatment) following release from incarceration. The current study is a pilot randomized control trial evaluating the effectiveness and feasibility of the peer mentorship intervention.

The investigators are conducting this study due to the high rates of relapse to opioid use following release from prison (up to 75% within 3 months) and difficulty that some formerly incarcerated individuals report in accessing effective treatments for opioid use disorder. The investigators hypothesize that having peer mentors - who themselves have experienced incarceration and have had success with buprenorphine treatment for opioid use disorder - assisting formerly incarcerated individuals in seeking treatment will result in higher rates of linkage to care in comparison to referral to a community health center for buprenorphine treatment.

In this 18-month randomized control trial of the BUP-FAST intervention, the investigators will recruit 72 formerly incarcerated individuals with opioid use disorder; half will then be randomized to receive the BUP-FAST intervention (peer mentorship); and the other half (control) will receive referral to a community health center for assessment for buprenorphine treatment. Medication will not be provided as part of this study. Participants will only receive buprenorphine treatment if they meet appropriate medical criteria after assessment at the community health center.

Enrollment: 13 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Current or prior (at the time of incarceration) opioid use disorder by DSM-V criteria
2. ≥ 18 years old
3. Fluent in English or Spanish
4. Released from incarceration in the last 4 weeks

Exclusion criteria

1. Current buprenorphine or methadone maintenance treatment
2. Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

13 participants in 2 patient groups

Referral to treatment (Control)

Active Comparator group

Description:

The control group will receive a referral to buprenorphine treatment by the research staff.

Treatment:

Behavioral: Referral to treatment

BUP-FAST Intervention

Experimental group

Description:

Thirty-six participants will each be paired with a trained peer mentor who will provide the BUP-FAST intervention.

Treatment:

Behavioral: BUP_FAST