Burn Coverage of Burn by Tilapia Fish Skin (TFS)

Aswan University

Status: Completed

Conditions: Tilapia Fish Skin in Burn Coverage

Treatments: Procedure: TFS

Study type: Observational

Funder types: Other

Identifiers

NCT06549569

696/11/22

Details and patient eligibility

About

The goal of this experimental study is to compare TFS and regular dressings as coverage for acute thermal burns. The main question it aims to answer is:

Is TFS effective in treating thermal burns? burn induction was done on rabbits to obtain second-degree thermal burn, followed by coverage with TFS

Full description

Nile Tilapia Fish Skin (NTFS) has been suggested as an option for biological material for the management of burns. Nile Tilapia Fish Skin also presented a large composition of type I collagen, morphology similar to human skin and high resistance and tensile extension at the break. We chose Baladi rabbits for their relatively ease of handling, accommodation and resistance to surgical aggressions and infectious processes, with low mortality. However, the choice of male rabbits is due to variations in hormonal cycles in females that could intervene in the process of tissue repair.

This experimental model was established to evaluate healing process and outcome results after application of Tilapia Fish Skin on acute contact thermal that was done in order to obtain injuries with the same size and depth.

Enrollment: 20 patients

Sex: Male

Ages: 1 year to 18 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• healthy male one year old rabbit

Exclusion criteria

• female unhealthy rabbits

Trial design

20 participants in 2 patient groups

TFS

Description:

thermal burn coverage with Tilapia fish skin

Treatment:

Procedure: TFS

regular dressing

Description:

thermal burn coverage with regular dressing

Treatment:

Procedure: TFS