Buspirone Plus Omeprazole for Functional Dyspepsia

Isfahan University of Medical Sciences

Status and phase: Completed; Phase 4

Conditions: Dyspepsia

Treatments: Drug: Buspirone; Drug: Placebo Oral Tablet

Study type: Interventional

Funder types: Other

Identifiers

NCT03444831

166681

Details and patient eligibility

About

This study is a double-blinded Randomised clinical trial aim to compare buspirone plus omeprazole with placebo plus omeprazole.

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• being over 18-year-old, Rome III criteria for FD
• normal upper endoscopy within five years
• negative Urease test for H-pylori
• acceptance informed concept form.

Exclusion criteria

• denied to get these medications
• taking other drugs for FD
• patients with the organic gastrointestinal disorder

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups, including a placebo group

Buspirone plus Omeprazole

Experimental group

Treatment:

Drug: Buspirone

Placebo plus Omeprazole

Placebo Comparator group

Treatment:

Drug: Placebo Oral Tablet