Butyrophilins Role in Colon Cancer

Institut Paoli-Calmettes

Status

Enrolling

Conditions

Colonic Cancer

Treatments

Biological: analysis of BTN and BTNL status

Study type

Interventional

Funder types

Other

Identifiers

IMMUNOCOL-IPC 2019-018

Details and patient eligibility

About

quantification of BTNL molecules in colon cancer in order to determinate if their could be used as a prognostic marquer

Enrollment

200 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient is older than 18 years old,
Signed participation consent,
Non-metastatic colon cancer immediately resectable or metastatic and liver synchronous for which it was decided a combined colic and liver surgery (metastatic patient at the outset) in multidisciplinary consultation meeting.
Performance Status (PS) 0 or 1
affiliated to the social security or beneficiary

Exclusion criteria

Rectal cancer, colon cancer recurrence
Emergency of colon cancer Surgery
History of inflammatory disease of the digestive tract (Crohn's disease or ulcerative colitis)
Patient who received neoadjuvant therapy other than chemotherapy
Patient treated with immune-suppressors or long-course corticosteroids <12 months
Pregnant women or likely to be pregnant (without effective contraception) or breastfeeding,
Person in urgent situation, person under legal protection measure, or unable to express his / her consent,
Impossibility of submitting to the medical examination of the test for geographical, social or psychological reasons