Bypass vs. Ecmo in Lung Transplantation (BELT)

NeuroTherapia, Inc.

Status

Terminated

Conditions

Lung Transplant; Complications

Treatments

Device: Cardiopulmonary Bypass

Device: Extracorporeal Membrane Oxygenation

Study type

Observational

Funder types

Other

Identifiers

NCT03021538

17-166

Details and patient eligibility

About

This study seeks to compare outcomes of 2 different methods of cardiopulmonary support during lung transplant surgeries.

Full description

This study will compare use of extracorporeal membrane oxygenation (ECMO) and heart-lung bypass (CPB) during lung transplant procedures and their short and long term outcomes.

Enrollment

13 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

The study population will be all patients requiring cardiopulmonary support while undergoing lung transplantation at our institution.

Exclusion criteria

Patients undergoing concomitant cardiac operations with indication for obligate use of cardiopulmonary bypass
Patient with specific anatomy that require full cardiac decompression such as severe pulmonary hypertension or large heart that are shifted severely into the left chest
Patients with high likelihood of significant pleural bleeding that will require returning the blood back into the cardiotomy reservoir
Patients bridged to transplant with ECMO
Cystic fibrosis/bronchiectasis/resistant infection patients where surgeon will need to remove both lungs prior to implantation
Patients who the surgeon feels would be better served with CPB rather than ECMO- These patients will be entered into a registry and followed.