C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance

Yale University

Status: Completed

Conditions: Glucose Intolerance

Study type: Observational

Funder types: Other

Identifiers

NCT00589355

12110

Details and patient eligibility

About

The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose intolerance compared to normal controls.

Enrollment: 46 patients

Sex: Female

Ages: 40 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy postmenopausal women
• ages 40-65

Exclusion criteria

• smokers
• diabetes requiring medication

Trial design

46 participants in 2 patient groups

1

Description:

postmenopausal women with glucose intolerance (either pre-diabetes or diet-controlled diabetes)

2

Description:

postmenopausal women with normal glucose tolerance