C-reactive Protein Levels Among Individuals With COVID-19

Henning Bliddal

Status: Completed

Conditions: Coronavirus Infection

Treatments: Diagnostic Test: C-reactive protein

Study type: Observational

Funder types: Other

Identifiers

NCT04373798

APPI2-CV-2020-02

Details and patient eligibility

About

The primary objective of this multi-center study is to clarify the value of a CRP measurement for triage of patients initially presenting with light symptoms of the COVID-19 infection.

Current recommendations of management of COVID-19 include large-scale tests for virus. Such tests reveal whether an individual is infected with the virus, however, the demonstration of virus per se has no prognostic value for the ensuing course of the COVID-19 disease. Publications of possible treatments strategies increase exponentially, while evidence of triage of the affected individuals is mainly based on the level of pulmonary affection as measured by the Oxygen saturation.

To inform decision making for which patients are to be hospitalized due to risk of developing more severe affection, this study addresses the question, whether triage may be performed with the aid of a simple CRP measurement.

Enrollment: 1,006 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. A test for COVID-19 taken at the check point
2. Signed, informed consent for blood test to be drawn for the Biobank

Exclusion criteria

1. Former admission to hospital for COVID-19
2. Direct admission from check point.

Trial design

1,006 participants in 1 patient group

Suspected COVID-19

Description:

Individuals with symptoms who are seen at covid19 check points for covid19 diagnosis.

Treatment:

Diagnostic Test: C-reactive protein