C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection

CSI College of Dental Sciences and Research, Madurai

Status: Unknown

Conditions: Dentoalveolar Abscess

Treatments: Procedure: ROOT CANAL TREATMENT

Study type: Interventional

Funder types: Other

Identifiers

NCT04684407

CSIDentalCMadurai

Details and patient eligibility

About

C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment

Full description

In patients with acute apical abscess C-reactive proteins are evaluated before and after root canal treatment. In this intra-canal medications calcium hydroxide and triple antibiotic paste are compared. PAI score of the corresponding tooth is noted .

Enrollment: 200 estimated patients

Sex: All

Ages: 16 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

patient with acute apical abscess

Exclusion criteria

• Teeth with evidence of previous initiated root canal treatment
• History of myocardial infarction, coronary heart disease
• Patients allergic to local anesthetic
• Patients under steroid medication
• Patients who are immunocompromised

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 2 patient groups

calcium hydroxide

Active Comparator group

Description:

calcium hydroxide powder is mixed with normal saline and placed as intra-canal medication

Treatment:

Procedure: ROOT CANAL TREATMENT

Triple antibiotic paste

Experimental group

Description:

Triple antibiotic paste (TAP)- combination of metronidazole,ciprofloxacin and minocycline mixed in a ratio of 1:1:1 . TAP paste is combined with propylene glycol and placed as intra canal medication.

Treatment:

Procedure: ROOT CANAL TREATMENT