Cabbage Leaf Wraps in Osteoarthritis of the Knee (KoGon)

Universität Duisburg-Essen

Status: Completed

Conditions: Osteoarthritis of the Knee

Treatments: Other: Cabbage leave wraps; Drug: Diclofenac Gel

Study type: Interventional

Funder types: Other

Identifiers

NCT02027792

13-5581 KoGon

Details and patient eligibility

About

This randomised controlled trial aims to investigate the efficacy of cabbage leaf cataplasms in the treatment of primary symptomatic osteoarthritis of the knee. 81 patients will be randomised into one of 3 groups and apply either cabbage leaf cataplasm or diclofenac gel daily for 4 weeks or receive only usual care. Efficacy will be measured using questionnaire on pain, disability, quality of life and pressure pain sensitivity.

Enrollment: 81 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteoarthritis of the knee, Kellgren Lawrence stadium 2-3
• at least 50% of days with complaints
• initial pain intensity 45mm on a 100mm visual analoge scale

Exclusion criteria

• medication with corticoids or immunsupressing drugs
• secondary arthritis/arthrosis
• operation to the knee within 12 months prior
• injection within 4 weeks (cortison) or 6 months prior (hyaluronic acid)
• severe comorbidities (liver, kidney, asthma, psychiatric disorders etc.)
• participation in other studies
• pregnancy, breastfeeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

81 participants in 3 patient groups

Cabbage leaf wraps

Experimental group

Description:

Daily application of cabbage leaf wraps over night, 4 weeks application

Treatment:

Other: Cabbage leave wraps

Diclofenac gel

Active Comparator group

Description:

daily application of diclofenac gel 4 weeks application

Treatment:

Drug: Diclofenac Gel

Usual care

No Intervention group

Description:

no specific intervention