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Caffein Consumption and Response Inhibition

U

Uppsala University

Status

Completed

Conditions

Eating Behavior
Obesity

Treatments

Drug: Caffeine
Drug: Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT01815203
PH2013a

Details and patient eligibility

About

With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy levels.

One of the factors that is potentially important in response inhibition is caffeine.

The aim is to assess the direct effects of caffeine on response inhibition, using a No Go/Go-task. We will also assess whether the presentation of food cues, i.e. as words or as pictures, modulate response inhibition different in restrained vs. non-restrained eaters.

Full description

In a blinded, randomized cross-over design, participants will receive either a capsule with caffeine or placebo at two separate occasions whereupon study tasks will be performed.

Enrollment

21 patients

Sex

Male

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Only males
  • 18 ≤ 35 years
  • Healthy (self rated)
  • Used to drink caffeine
  • Used to eat breakfast regularly (≥ 5 times a week).
  • Non-smokers

Exclusion criteria

  • BMI outside the range of 18,5 ≤ 25
  • hypersensitivity for the ingredients of the foods under study
  • being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea
  • Presence of any chronically disease and/or treatment with medication

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

21 participants in 2 patient groups, including a placebo group

Caffeine
Experimental group
Description:
Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test.
Treatment:
Drug: Caffeine
Placebo
Placebo Comparator group
Description:
Administration of placebo (one gelatin capsule containing starch) with subsequent cognitive tasks and food test.
Treatment:
Drug: Placebo

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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