Caffeine and Resistance Training in Older Adults

Alberto Pérez-López

Status: Invitation-only

Conditions: Caffeine and Resistance Training

Treatments: Dietary Supplement: Placebo + Resistance exercise; Dietary Supplement: Caffeine + Resistance exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT06618261

CEIP/2022/3/055

Details and patient eligibility

About

Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to strength training.

Objectives: The present study aims to analyze the effects of acute and chronic caffeine intake on neuromuscular adaptations to strength training, according to sex (men vs. women) and type of exercise (bench press vs. squat), as well as fatigue perception, mood state, and potential side effects in older adults.

Enrollment: 48 estimated patients

Sex: All

Ages: 55+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between ≥ 55
• Body mass index (BMI) ≥ 30 kg/m².
• Physically active subjects (>150 min/week of moderate exercise).
• Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
• Participants capable of performing the tests.

Exclusion criteria

• History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
• Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
• Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
• Performing strenuous exercise within 48 hours prior to the tests.
• Failing to replicate the same food intake on the two experimental days.
• Consuming caffeine after 6 PM on the day prior to training or testing.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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48 participants in 4 patient groups, including a placebo group

Caffeine - Males

Experimental group

Treatment:

Dietary Supplement: Caffeine + Resistance exercise

Placebo - Males

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo + Resistance exercise

Caffeine - Females

Experimental group

Treatment:

Dietary Supplement: Caffeine + Resistance exercise

Placebo - Females

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo + Resistance exercise