Caffeine and Sodium Citrate Ingestion

Swiss Paraplegic Research, Nottwil

Status: Completed

Conditions: Lactic Acid/Metabolism; Heart Rate/Drug Effects; Wheelchairs; Physical Education and Training/Methods; Dietary Supplements

Treatments: Dietary Supplement: Mannitol; Dietary Supplement: Caffeine; Dietary Supplement: Sodium Citrate; Dietary Supplement: Sodium Chloride

Study type: Interventional

Funder types: NETWORK

Identifiers

NCT01591226

2012-02

Details and patient eligibility

About

A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.

The aim of the study is to investigate whether caffeine or sodium citrate ingestion could enhance performance in spinal cord injured wheelchair athletes. It is a double blind, placebo controlled and randomized study.

Full description

The athletes have to complete four 1500m tests on a training roller. Before each treatment they get different supplementations. Once they get sodium citrate and a placebo, once caffeine and a placebo, once sodium citrate and caffeine and for the fourth treatment they get twice a placebo. Two hours after starting with the supplementation they have to complete the 1500m as fast as possible. Time to complete 1500m, blood pH, plasma bicarbonate, sodium concentration, heart rate, oxygen consumption, blood lactate concentration and rate of perceived exertion (RPE) were measured.

Enrollment: 9 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• wheelchair athletes
• national team
• category T53 and T54

Exclusion criteria

• medicated
• pregnant (for women)
• cardiovascular and respiratory diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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9 participants in 4 patient groups, including a placebo group

Caffeine

Active Comparator group

Description:

6mg per kg bodyweight ingested 60min before test

Treatment:

Dietary Supplement: Caffeine

Dietary Supplement: Sodium Chloride

Placebo

Placebo Comparator group

Description:

Sodium chloride and mannitol as placebo are ingested by the athlete

Treatment:

Dietary Supplement: Mannitol

Dietary Supplement: Sodium Chloride

Sodium Citrate

Active Comparator group

Description:

sodium citrate diluted in 7dl water, ingestion 120 to 90min prior test

Treatment:

Dietary Supplement: Mannitol

Dietary Supplement: Sodium Citrate

Caffeine and Sodium Citrate

Active Comparator group

Description:

sodium citrate 120-90min prior test capsules:60min prior test

Treatment:

Dietary Supplement: Caffeine

Dietary Supplement: Sodium Citrate