Caffeine and the Autonomic Nervous System

LMU Klinikum

Status: Unknown

Conditions: Autonomic Nervous System Imbalance

Treatments: Dietary Supplement: caffeine

Study type: Interventional

Funder types: Other

Identifiers

NCT04886869

CaffeineLMU

Details and patient eligibility

About

Caffeine consumption has been linked to dysfunction of the autonomic nervous system. In this study the investigators analyze the effects of caffeine containing drinks (including energy drinks and coffee) on ECG based parameters of the autonomic nervous system.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy individuals
• > 18 years

Exclusion criteria

• known cardiovascular disease
• other diseases which may influence the autonomic nervous system
• medication which may influence the autonomic nervous system
• prior caffeine consumption (<24 hours)

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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20 participants in 3 patient groups, including a placebo group

Coffee

Experimental group

Description:

Oral consumption of 3 cups of coffee containing 240 mg caffeine

Treatment:

Dietary Supplement: caffeine

Energy drink

Experimental group

Description:

Oral consumption of 750 mL of a commercial energy drink containing 240 mg caffeine

Treatment:

Dietary Supplement: caffeine

Placebo

Placebo Comparator group

Description:

Oral consumption of 750 mL water

Treatment:

Dietary Supplement: caffeine