Caffeine Consumption and Mortality in Diabetes

João Sérgio Neves

Status: Completed

Conditions: Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT03367806

Caffeine-DM

Details and patient eligibility

About

Previous studies suggested an inverse relationship between coffee consumption and mortality in the general population. Furthermore, an inverse association between coffee consumption and serum biomarkers of inflammation and insulin resistance has been described. Prospective studies showed that coffee consumption might be associated with reduction in the incidence of type 2 diabetes. Although caffeine consumption appears to be associated with a decreased risk of developing type 2 diabetes, the relationship between caffeine consumption and mortality in patients with diabetes remains uncertain. The current analysis aimed to assess the effects of caffeine consumption and caffeine source on all-cause, cardiovascular and cancer mortality among patients with diabetes.

Enrollment: 3,052 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• NHANES participants from 1999 to 2010 above 18-year old, with diagnosis of diabetes

Exclusion criteria

• Implausible alimentary reports (defined as consumption of less than 500 kcal/day or more than 3500 kcal/day)
• Missing information on caffeine consumption
• Missing information on mortality