Caffeine Versus Placebo for Spinal Headaches

United States Naval Medical Center, Portsmouth

Status: Withdrawn

Conditions: Post Dural Puncture Headache

Treatments: Drug: Caffeine; Drug: saline

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00809627

CIP 2006 0051

Details and patient eligibility

About

Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").

Full description

Pain will be assessed at set intervals using a Visual Analog Scale. Blood patch therapy will be offered to all those still in pain at the end of one hour after drug administration.

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosed with post dural puncture headache

Exclusion criteria

• age < 18
• pregnant
• allergic to caffeine
• cardiac or peripheral vascular disease
• uncontrolled hypertension

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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0 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

IV caffeine with saline and opiate

Treatment:

Drug: Caffeine

2

Placebo Comparator group

Description:

IV saline with opiate

Treatment:

Drug: saline