Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Hillel Yaffe Medical Center

Status: Begins enrollment in 4 months

Conditions: Neonatal Early-onset Sepsis

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06643052

0121-20-HYMC-IL

Details and patient eligibility

About

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.

Full description

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedical center.

Enrollment: 6,300 estimated patients

Sex: All

Ages: Under 7 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newborn unfants born in Hillel Yaffe medical center
• 35 weeks of gestation or more
• Blood culture was taken

Exclusion criteria

• Sepsis workup for other reason
• 34 weeks of gestation or less

Trial design

6,300 participants in 2 patient groups

Before calculator

Description:

Newborn infants before assimilation of EOS calculator

Treatment:

Other: No intervention

With calculator

Description:

Newborn infants after assimilation of EOS calculator

Treatment:

Other: No intervention