Calcium Ionophore Solution Can Increase Fertilization Rate in Patients During Intracytoplasmic Sperm Injection(ICSI) Who Have Poor Ovarian Reserve?

Baskent University

Status: Unknown

Conditions: Fertilization Failure

Treatments: Other: calcium ionophore solution

Study type: Interventional

Funder types: Other

Identifiers

NCT02045914

KA1-191

Details and patient eligibility

About

The aim of this study is to evaluate calcium ionophore solution on fertilization rate of patients during intracytoplasmic sperm injection who have poor ovarian reserve

Full description

During ICSI cycle , female patients who have poor ovarian reserve have low oocyte numbers. So by calcium ionophore solution which we know that it can increase fertilization rate in males who have azospermia or globozoospermia. we planned to check if this solution can increase fertilization rate also in poor ovarian reserve patients?

Enrollment: 162 estimated patients

Sex: Female

Ages: 23 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• infertile couples who have no male factor infertility
• infertile females who are poor ovarian reserve

Exclusion criteria

• infertile couples who have male factor infertility
• infertile female who have endometriosis

Trial design

162 participants in 2 patient groups

control group

No Intervention group

Description:

the patients who have no intervention with calcium ionophore during ICSI cycle

calcium ionophore

Experimental group

Description:

the patients whose oocytes are incubated with calcium ionophore solution during ICSI cycle

Treatment:

Other: calcium ionophore solution