Calorie Anticipation and Food Intake

Uppsala University

Status: Completed

Conditions: Obesity; Eating Behaviour

Treatments: Behavioral: low calorie yogurt; Behavioral: high calorie yogurt

Study type: Interventional

Funder types: Other

Identifiers

NCT01680315

PH2012

Details and patient eligibility

About

The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food. Food intake is not only regulated by appetite and satiety signals - external cues also play an important role.

It has been observed that food intake and the pleasure derived from consumption is affected by manipulation of the external cues.

The investigators will assess the contribution of food anticipation (calorie information) and actual consumption of a test food (calorie intake) on in satiety responses (such as ghrelin responses, appetite and subsequent food intake). The investigators expect the information on the amount of calories, rather than the actual amount of calories in the food, to predict the ghrelin responses and the subsequent intake of a second meal.

Full description

In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order.

Enrollment: 12 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female
• healthy
• being used to eat breakfast regularly (≥ 5 times a week).

Exclusion criteria

• hypersensitivity for the ingredients of the foods under study;
• lack of appetite; following an energy-restricted diet or change in body weight > 5 kg; or
• being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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12 participants in 2 patient groups

Calorie information

Experimental group

Description:

Low calorie yogurt High calorie yogurt with low calorie information sheet

Treatment:

Behavioral: low calorie yogurt

Behavioral: high calorie yogurt

Calorie information (high)

Experimental group

Description:

Low calorie yogurt High calorie yogurt High calorie information sheet

Treatment:

Behavioral: low calorie yogurt

Behavioral: high calorie yogurt