Calprotectin Levels in Necrotizing Enterocolitis

Ankara Yildirim Beyazıt University

Status: Completed

Conditions: Necrotising Enterocolitis Neonatal

Study type: Observational

Funder types: Other

Identifiers

NCT06693154

26379996/26, 03-2022

Details and patient eligibility

About

Necrotizing enterocolitis (NEC) is a serious condition that can affect premature babies, leading to complications like intestinal damage and infection. In our study, we measured specific markers (called calprotectin) in blood and stool to understand how severe NEC is and predict outcomes. We found that these markers were higher in babies with more severe NEC (stage 3), especially in those who needed surgery or sadly did not survive. This information can help doctors detect NEC earlier, understand its severity, and make better decisions for treating affected babies.

Enrollment: 59 patients

Sex: All

Ages: 3 to 30 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

before 32 weeks of gestation with a birth weight of ≤1500 grams

Exclusion criteria

Infants whose families did not provide consent and those with congenital anomalies were excluded.

Trial design

59 participants in 1 patient group

Premature infants diagnosed with stage 2 and stage 3 NEC and a matched control group.