Cambridge Anti-Myopia Trial: Accommodation Training and Aberration Control in Myopia Development

Anglia Ruskin University

Status and phase: Completed; Phase 2

Conditions: Myopia

Treatments: Device: Aberration controlled contact lens; Behavioral: Vision training

Study type: Interventional

Funder types: Other

Identifiers

NCT00317551

VisionCRC-ARU

Details and patient eligibility

About

We have identified focussing problems related to myopia getting worse. Our trial uses optical and orthoptic interventions that correct the focussing problems to see if this retards myopia progression.

Full description

Myopia is a burgeoning health and social problem. Currently there is no acceptable clinical treatment that prevents progression. This study is a double masked placebo controlled block randomized clinical trial of two interventions, to treat accommodative factors we have identified as being significantly correlated to myopia progression (rather than to the presence of myopia). We have shown that the interventions normalise the accommodative factors, and this trial examines the effect of these interventions on myopia progression.

Sex: All

Ages: 14 to 21 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Best corrected visual acuity of 6/5 in each eye
• Myopia in each meridian of at least 0.50 D
• Willingness to give consent
• Willingness to undertake any treatment option

Exclusion criteria

• History of systemic/ocular pathology
• History of any ocular surgery
• More than 10D of myopia
• Astigmatism more than 1.00 D

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind