Can 3D Kinematic Parameters Assess the Symptomatic and Functional Severity of KOA?

Guangzhou General Hospital of Guangzhou Military Command

Status: Completed

Conditions: Osteoarthritis,Knee

Treatments: Procedure: Observational procedure

Study type: Observational

Funder types: Other

Identifiers

NCT03011112

GuangzhouGH003

Details and patient eligibility

About

There is little study focusing on kinematic parameters in the assessment of the symptomatic and functional severity of knee osteoarthritis (KOA). The purpose of this study is to evaluate the correlations between kinematic parameters and the severity of symptoms and functions in patients with KOA.

Enrollment: 186 patients

Sex: All

Ages: 50 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. age> 50 years
2. body mass index<30;
3. confirmed radiographically and assessed according to KL score;
4. knee pain in their knees at least three months;
5. absolute medial compartment KOA according to atlas criteria13;
6. able to walk unaided

Exclusion criteria

1. history of knee surgery;
2. Corticosteroid or Sodium Hyaluronate injection within 6 months;
3. neuropathic arthropathy or rheumatoid arthritis;
4. any other muscular or neurological diseases that affected the condition of the lower limbs;
5. any treatments or training (e.g. kneepad) to improve the symptoms of KOA;
6. history of foot/ankle/hip injury or disease;
7. unable to walk independently;
8. history of heart disease;
9. lateral KOA according to atlas criteria13;
10. body mass index> 30;
11. age> 90 years;
12. unable to finish the procedure

Trial design

186 participants in 4 patient groups

KL 1

Description:

All patients (\>50 years) are classified to be Kellgrence/Lawrence grade 1 according to Kellgrence/Lawrence score.

Treatment:

Procedure: Observational procedure

KL 2

Description:

All patients (\>50 years) are classified to be Kellgrence/Lawrence grade 2 according to Kellgrence/Lawrence score.

Treatment:

Procedure: Observational procedure

KL 3

Description:

All patients (\>50 years) are classified to be Kellgrence/Lawrence grade 3 according to Kellgrence/Lawrence score.

Treatment:

Procedure: Observational procedure

KL 4

Description:

All patients (\>50 years) are classified to be Kellgrence/Lawrence grade 4 according to Kellgrence/Lawrence score.

Treatment:

Procedure: Observational procedure