Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

National Taiwan University

Status: Unknown

Conditions: Kidney Failure, Chronic

Treatments: Drug: vitamin C, intravenous injection

Study type: Interventional

Funder types: Other

Identifiers

NCT00172302

930105

Details and patient eligibility

About

Intravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients

Full description

Melanogenesis is caused by enzymatic conversion of tyrosine to melanin pigments.Ascorbic acid has the ability to inhibit peroxidase and may thus inhibit melanin synthesis.

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• chronic hemodialysis patients

Exclusion criteria

• allergic to vitamin C, using steroid, etc

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind