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Can Japanese Traditional Foods Lower Blood Pressure in Healthy Volunteers (Horenso)

K

Kyorin University

Status

Completed

Conditions

Blood Pressure

Treatments

Dietary Supplement: traditional Japanese diet

Study type

Interventional

Funder types

Other

Identifiers

NCT00928824
KyorinU

Details and patient eligibility

About

The purpose of this study is to determine whether traditional japanese diet blood pressure in healthy volunteers.

Full description

Japanese traditional diet contains considerably more nitrate/nitrite than the European foods. 80% of dietary nitrate originates from vegetables. Green leafy vegetables, especially spinach, salad and seaweed are rich in nitrates. Other vegetables contain nitrate at lower concentrations, but because they are consumed in greater quantity, they may contribute more nitrate and thus nitrite from the diet. Nitrate/nitrite is attributed multiple health benefits. Japanese people have an exceptional longevity and the lowest rate of heart diseases. On the other hand, gastric cancer rate is high too. Nitrate/nitrite is strongly correlated with these phenomena. Is this high nitrate consumption protective or damaging? Understanding dietary nitrite and nitrate consumption and its metabolism therefore becomes very important.

Aim: To compare conversion of nitrate to nitrite in Japanese people, measured in blood and in saliva during consumption of traditional Japanese foods vs European diet.

Enrollment

25 patients

Sex

All

Ages

20+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy volunteers

Exclusion criteria

  • high/low blood pressure

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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