Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?

Başakşehir Çam & Sakura City Hospital

Status: Completed

Conditions: Hemodynamic Instability; Shock, Septic

Treatments: Procedure: Measurement of hemodynamic parameters.

Study type: Observational

Funder types: Other

Identifiers

NCT06415006

2023-24-20

Details and patient eligibility

About

We evaluated the ability of shock indices and hemodynamic parameters to predict 28-day ICU mortality.

Full description

Shock indices and hemodynamic parameters are significant determinants of mortality in adult ICU patients. This study aimed to evaluate the potential of four known shock indices Shock Index (SI), Age-adjusted Shock Index (aSI), Diastolic Shock Index (dSI), and hemodynamic parameters including Heart Rate (HR), Systolic Arterial Blood Pressure (ABPsys), Diastolic Arterial Blood Pressure (ABPdias), and Mean Arterial Blood Pressure (ABPmean) in predicting 28-day ICU mortality in patients diagnosed with sepsis and septic shock.

Enrollment: 1,522 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with a preliminary diagnosis of sepsis/septic shock in the intensive care unit
2. Adult patients aged between 18 and 80 years

Exclusion criteria

1. Patients under 18 years old
2. Pregnant patients
3. Patients suspected of having COVID-19 pneumonia
4. Patients with incomplete data
5. Patients for whom outcome information is unavailable due to referral to an external center
6. Patients with confirmed COVID-19, validated by thoracic computed tomography images and nasal swab PCR results
7. Patients discharged from the intensive care unit within 24 hours

Trial design

1,522 participants in 1 patient group

Group Sepsis

Description:

The group consists of 1,522 patients treated in the intensive care unit for sepsis/septic shock.

Treatment:

Procedure: Measurement of hemodynamic parameters.