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Canderel:Effects on Blood Glucose Concentration and Appetite Scores

K

King's College London

Status

Unknown

Conditions

Appetitive Behavior
Glucose Metabolism Disorders

Treatments

Dietary Supplement: Canderel drink
Dietary Supplement: Canderel+Lyle's Golden Syrup drink

Study type

Interventional

Funder types

Other

Identifiers

NCT03232008
KCLMScNutr2017

Details and patient eligibility

About

This study investigates the effects of Canderel, an aspartame and acesulfame-k blend artificial sweetener powder, on post-postprandial blood glucose levels and appetite scores.

Full description

The study is separated into two parts: A) investigating the effects of artificial sweeteners in combination with complex carbohydrates; and B) investigating the effects of artificial sweeteners in combination with simple sugars.

A) Participants will be randomly given either the placebo drink (3g of maltodextrin dissolved in 250ml of water) or the Canderel drink (3g of Canderel dissolved in 250ml of water) alongside an isocaloric high carbohydrate breakfast. Blood glucose measurements will be obtained through finger pricking and appetite will be measured using self-reported visual analog scores rating hunger, desire to eat, fullness and alertness for up to 3 hours after breakfast.

B)Participants will be randomly given either the placebo drink (3g of Lyle's Golden syrup and 3g of maltodextrin dissolved in 250ml of water) or the Canderel+sugars drink (3g of Canderel and 3g of Lyle's Golden syrup dissolved in 250ml of water) . Blood glucose measurements will be obtained through finger pricking and appetite will be measured using self-reported visual analog scores rating hunger, desire to eat, fullness and alertness for up to 3 hours after drink

Enrollment

110 patients

Sex

All

Ages

18 to 64 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Healthy male and female adults (18-64)

Exclusion criteria

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

110 participants in 4 patient groups

Experiment A- experimental
Experimental group
Description:
3g Canderel in 250ml water
Treatment:
Dietary Supplement: Canderel drink
Experiment A- control
No Intervention group
Description:
3g of maltodextrin in 250 ml of water
Experiment B- experimental
Experimental group
Description:
3g Canderel + 35g Lyle's Golden Syrup in 250 ml water
Treatment:
Dietary Supplement: Canderel+Lyle's Golden Syrup drink
Experiment B- control
No Intervention group
Description:
3g Lyle's Golden Syrup + 35g of maltodextrin in 250 ml of water

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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