Candesartan Cilexetil Special Drug Use Surveillance 「Challenge - Quality Control」

Takeda

Status: Completed

Conditions: Hypertension

Treatments: Drug: Candesartan Cilexetil

Study type: Observational

Funder types: Industry

Identifiers

NCT02211638

JapicCTI-132380 (Registry Identifier)

460-017

JapicCTI-R171021 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to gain an understanding of the actual use of candesartan cilexetil (Blopress) in patients with hypertension, and to examine the changes in parameters such as blood pressure.

Full description

This special drug use surveillance was planned to gain an understanding of the actual use of candesartan cilexetil in the new anti-hypertensive treatment environment where angiotensin receptor blocker (ARB) combination drugs have become commercially available. The surveillance also investigated the background factors of patients continuing treatment with candesartan cilexetil and patients who switched from candesartan cilexetil to ARB combination drugs, as well as changes in parameters such as blood pressure.

The usual adult dosage of Candesartan cilexetil is 4 to 8 mg, administered orally, once daily. Meanwhile, treatment was to be started at 2 mg once daily in patients with renal impairment and the dose could be increased up to 8 mg as necessary.

Enrollment: 18,113 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hypertensive patients

Exclusion criteria

1. Inpatients
2. Patients under dialysis (planned)
3. Patients with a history of coronary artery disease/cerebrovascular disorder within 6 months
4. Patients with ≥ class III of the New York Heart Association (NYHA) classification functional classification of heart failure
5. Patients that have been prescribed with candesartan (this drug/Ecard/Unisia) in the past
6. Patients who are pregnant or may possibly become pregnant

Trial design

18,113 participants in 1 patient group

Candesartan Cilexetil tablets (2 to 12 mg)

Description:

Candesartan Cilexetil tablets (2 to 12 mg), orally, once daily for up to 3 months

Treatment:

Drug: Candesartan Cilexetil