A Brief Intervention for Cannabis Use (Bloom)

Medical University of South Carolina (MUSC)

Status: Enrolling

Conditions: Cannabis Use Disorder

Treatments: Behavioral: Health Education (HealthEdu); Behavioral: Bloom

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06395389

K23DA058077 (U.S. NIH Grant/Contract)

Pro00133931

Details and patient eligibility

About

The purpose of this study is to compare two brief interventions targeting potentially problematic cannabis use in emerging adults (ages 18-25). Brief interventions are two 40-50 minute sessions separated by 1 week. Eligible emerging adults will complete a detailed cannabis assessment (biological and self-report), followed by one of the two brief interventions, and three follow-up assessments: one immediately after the second session and at 1- and 3-months post-intervention. Assignment to the brief intervention is random. Salivary samples will be collected at baseline, post-intervention, and both follow-ups, for a total of 4 samples, to be tested for tetrahydrocannabinol (THC) and cannabidiol (CBD).

Full description

Cannabis is the most widely used federally illicit substance among emerging adults (age 18-25) in the U.S., and frequent cannabis use is associated with myriad long-term health, social, and academic/occupational consequences. Despite this, rates of perceived risk of daily/regular cannabis use have steadily declined over the past two decades, and this is associated with increased frequency of use, a risk for for Cannabis Use Disorder (CUD). Brief interventions (BIs) are among the most frequently used approaches for addressing problematic or potentially problematic substance use in non-treatment-seeking adolescents and young adults. Although several cannabis brief interventions have been developed and tested to date, meta-analyses indicate that the efficacy of these interventions for emerging adults is mixed and the quality of studies is low, suggesting that novel approaches and rigorous methodology are necessary to improve efficacy. The current study will evaluate the feasibility, acceptability, and preliminary efficacy of a novel cannabis BI for emerging adults who frequently use cannabis.

Enrollment: 62 estimated patients

Sex: All

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ages 18-25
• Self-Report report cannabis use on at least 20 days of the past 30 days.
• Completion of an Intake Visit (PRO #94743)
• Submit a positive urine cannabinoid test during the Intake Visit

Exclusion criteria

• Currently engaged in substance use treatment for any type of substance use or currently treatment seeking
• History of substance use treatment for any type of substance
• Severe alcohol use disorder or presence of any substance use disorder (SUD) requiring a higher level of care
• Significant or acutely unstable medical or psychiatric problems (i.e., psychosis, mania) that would contraindicate research procedures, interfere with safety, compromise data integrity, or preclude consistent study participation
• Significant risk of suicide or homicide

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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62 participants in 2 patient groups

Health Education (HealthEdu)

Active Comparator group

Description:

Brief intervention providing recommendations/advice for good sleep hygiene, nutrition and physical activity, stress, and relationships.

Treatment:

Behavioral: Health Education (HealthEdu)

Bloom

Experimental group

Description:

Brief intervention providing personalized discussion of values/goals, reasons for cannabis use, and strategies to help live in line with values and achieve goals.

Treatment:

Behavioral: Bloom