Cantharone for the Treatment of Perenial Warts
Status and phase
Conditions
Treatments
Details and patient eligibility
About
Comparison of trichloroacetic acid versus cantharidine for the treatment of perenial warts.
Full description
Warts are one of the most common sexually transmitted diseases. They are caused by the human papilloma virus (HPV) that causes cervical cancer. Warts can grow, obstruct labor, and spread. Patients presenting to the obgyn clinic with perenial warts were randomized to treatment with trichloroacetic acid (one of the many types of treatments) or to the treatment with cantharidine group. Cantharidine is a vesicant extracted from beetle bugs which painlessly causes a small blister to form and cures the patient from the HPV infection causing the wart . We compared cosmesis, scar formation, pain and number of treatments (visits) as well as effectiveness in both groups.
Objectives
Determine if cantharone is more effective than trichloroacetic acid (TCA) for removal of warts Compare pain levels (pain during application) for each method Compare patient satisfaction for each method Compare scar formation and cosmesis for each method
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Warts on the perenial area
- Less than 4mm across.
Exclusion criteria
- Pregnancy
- Less than 18 years old
- Lesions larger than 4 millimeters across
- Unclear diagnosis
- Internal warts
- Diabetes
- HIV
- Warts within 2 cm of mucosal areas
Trial design
Primary purpose
Allocation
Interventional model
Masking
12 participants in 2 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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